Dr. Diab’s Publications @ Colorado Integrative Cancer Care

Diab SG, Castles CG, Fuqua SAW. Role of Altered Estrogen Receptors in Breast Cancer. In Vedeckis WV, (ed.): Hormone and Cancer. Birkhauser, Boston 1996. Pp 261-281, 1996
Diab SG, Yu Y-Y, Hilsenbeck SG, Allred DC, and Elledge RM. WAF1/CIP1 Protein Expression In Human Breast Cancer. Breast Cancer Research and Treatment 43: 99-103, 1997
Diab SG, Hilsenbeck S, De Moor C, Clark GM, Osborne CK, Ravdin P, and Elledge RM. Radiation Therapy and Survival in Breast Cancer Patients with 10 or More Positive Auxiliary Lymph Nodes Treated with Mastectomy. Journal of Clinical Oncology, 16: 1655-1660, 1998
Sami G. Diab, Sharyn D. Baker, Amita Joshi, Howard A. Burris, Patrick W. Cobb, Miguel A. Villalona-Calero, S. Gail ckhardt, Geoffrey R. Weiss, Gladys I. Rodriguez, Ronald Drengler, Maura Kraynak, Lisa Hammond, Michael Finizio, Daniel D. Von Hoff, and Eric K. Rowinsky. A Phase I and Pharmacokinetic Study of Losoxantrone and Paclitaxel in Patients with Advanced Solid Tumors. Clinical Cancer Research, 5: 299-308, 1999
Diab SG, Clark GM, Libby A, Allred DC, Osborne CK, and Elledge RM. Tumor Characteristics and Clinical Outcome of Tubular and Mucinous Breast Carcinoma. Journal of Clinical Oncology 17: 1442-1448, 1999
Sami G. Diab, Susan G. Hilsenbeck, Elzbieta Izbicka, Steve Weitman and Daniel D. Von Hoff. Significant Activity of a Novel Cytotoxic Agent, LY295501, Against a Wide Range of Tumors in the Human Tumor Cloning System. Anti-Cancer Drugs, 10: 303-307, 1999
Sami G. Diab, Richard M. Elledge, Gary M. Clark. Tumor Characteristics and Clinical Outcome of Elderly Patients with Breast Cancer. Journal of the National Cancer Institute 92, 550-556, 2000
Sharma S, and Diab SG. Are We Just Specialists or Is It Time For Us to Broaden Our Horizons in Treating The Cancer Patient? Seminars in Oncology. 24(5), 1997
Britten CD, Rowinsky EK, Baker SD, Agarwala SS, Eckardt JR, Barrington R, Diab SG, Hammond LA, Johnson T, Villalona-Calero M, Fraass U, Statkevich P, Von Hoff DD, Eckhardt SG. A Phase I and pharmacokinetic study of temozolomide and cisplatin in patients with advanced solid malignancies. Clin Cancer Res. 1999 Jul;5(7):1629-37.
Hidalgo M, Villalona-Calero MA, Eckhardt SG, Drengler RL, Rodriguez G, Hammond LA, Diab SG, Weiss G, Garner AM, Campbell E, Davidson K, Louie A, O’Neil JD, von Borstel R, Von Hoff DD, Rowinsky EK . Phase I and pharmacologic study of PN401 and fluorouracil in patients with advanced solid malignancies.
J Clin Oncol 2000 Jan;18(1):167-77

ORAL PRESENTATIONS AT NATIONAL AND INTERNATIONAL MEETINGS:

Radiation therapy improves survival by decreasing local failure in breast cancer patients with 10 or more positive auxiliary lymph nodes treated with mastectomy. SG Diab, CA de Moor, GM Clark, CK Osborne, PM Ravdin, RM Elledge. Meeting of the American Society of Medical Oncology, Denver, 1997
Does radiotherapy have an impact on systemic relapse. G Clark, SG Diab, S Hilsenbeck. Presented at the 20th International Congress of Chemotherapy. Sydney, Australia, 7/97.

Abstracts:

Annual San Antonio Breast Cancer Symposium 1996 and 1997

Diab SG, deMoor CA, Clark GM, Elledge RM. Adjuvant Local Radiation Therapy and Survival in Breast Cancer Patients with 10 or More Positive Lymph Nodes. Presented at the 19th Annual San Antonio Breast Cancer Symposium, 1996
Diab SG*, Clark GM, Libby A, Allred DC, Osborne CK, and Elledge RM. Tumor Characteristics and Clinical Outcome of Tubular and Mucinous Breast Carcinoma. Presented at the 20th Annual San Antonio Breast Cancer Symposium, 1997

American Society of Clinical Oncology meeting, 1997

SG Diab, CA de Moor, GM Clark, CK Osborne, PM Ravdin, RM Elledge. Radiation therapy improves survival by decreasing local failure in breast cancer patients with 10 or more positive auxiliary lymph nodes treated with mastectomy. (oral presentation).
SG Eckhardt, Y Atkins, SS Agarwala, J Eckardt, S. Diab, M Dugan, P Reidenberg, P Statkevich, M Kraynak, DD Von Hoff and EK with Cisplatin (CDDP) in Patients with Advanced Cancer. Cancer Therapy and Research Center, San Antonio, TX, University of Pittsburgh, Pittsburgh, PA and Schering-Plough, Kenilworth, NJ.

American Society of Clinical Oncology meeting, 1998

S Diab, C Britten, G Eckhardt, L Hammond, R Elledge, L Siu, S Sharma, M Hidalgo, C Aylesworth, B Razvillas, M Kraynak, S Baker, R Smith, S Averbuch, D Von Hoff, and E Rowinsky: Phase I and Pharmacokinetic (PK) Study of the Nonpolyglutamated Thymidylate Synthase (TS) Inhibitor ZD9331 Given as a 30 Minute Infusion Every 3 Weeks. Cancer Therapy and Research Center, University of Texas Health Science Center, Brooke Army Medical Center, San Antonio, TX and Zeneca Pharmaceuticals, Wilmington, DE. (poster discussion)
P Khoury, M Villalona-Calero, J Blum, S Diab, R Elledge, M Kraynak,- J Moczygemba, P Kromelis, I Morales, C Brown, T Griffin, D Von Hoff, E Rowinsky: Phase I Study of Capecitabine in Combination with Paclitaxel in Patients with Previously Treated Metastatic Breast Cancer. The University of Texas Health Science Center and Cancer Therapy & Research Center, San Antonio, TX, PRN Research, Dallas TXS, and Hoffman-La Roche LTD. Nutley, New Jersey.
L Hammond, M Villalona-Calero, SG Eckhardt, R Drengler, C Aylesworth, T Johnson, M Hidalgo, G Rodriguez, S Diab, P Monroe, D Thornton, D Von Hoff, and E Rowinsky. A Phase I and Pharmacokinetic (PK) Study of the Multitargeted Antifol (MTA) LY231514 with Folic Acid. Cancer Therapy and Research Center and Brooke Army Medical Center, San Antonio, TX and Eli Lilly Company, Indianapolis, IN. Presented at the American Society of Clinical Oncology Meeting, 1998

10th NCI-EORTC Symposium on New Drugs in Cancer Therapy, Amsterdam, 1998

S Diab, SD Baker, L Hammond, M Villalona-Calero, SG Eckhardt, C Tin-U, G Weiss, M Kraynak, C Aylesworth, L Smith, G Rodriguez, R Drengler, R Patil, L Siu, M Rothenberg, L Smetzer, E Nyhart, AM Sorniolo, D Von Hoff, and E Rowinsky. Phase I and Pharmacokinetic (PK) Study of the Diarylsulfonylurea LY295501 Administered as a single oral dose weekly for 3 weeks every 4 weeks. Cancer Therapy and Research Center, University of Texas Health Science Center, Brooke Army Medical Center, San Antonio, TX; Eli Lilly and Company, Indianapolis, IN
M Villalona-Calero, J Blum, S Diab, R Elledge, P Khoury, M Kraynak, J Moczygemba, P Kromelis, K Impellizeri, T Griffin, D Von Hoff, E rowinsky. Phase I Study of Capecitabine in Combination with Paclitaxel in Patients with Previously Treated Metastatic Breast Cancer. Cancer Therapy and Research Center, San Antonio, TX, PRN Research, Dallas TX, and Hoffman-LaRoche, Nutley, NJ
L Hammond, SD Baker, M Villalona-Calero, SG Eckhardt, R Drengler, C Aylesworth, T Johnson, M Hidalgo, G Rodriguez, S Diab, P Monroe, D Thornton, R Johnson, D Von Hoff, and E Rowinsky. A Phase I and Pharmacokinetic (PK) Study of the Multitargeted Antifol (MTA) LY231514 with Folic Acid (FA). Cancer Therapy and Reserach Center and Brooke army Med Center, San Antonio TX, and Eli Lilly Companym Inidanapolis, IN
M Hidalgo, MA Villalona-Calero, C Britten, L Siu, R Drengler, L Hammond, S Diab, E Campbell, A Louie, J O’Neil, D Von Hoff, and E Rowinsky. A Phase I and Pharmacokinetic (PK) Study of PN401 as a Rescue Agent for Escalating Doses of 5-Fluorouracil (5-FU) in Patients (PTS) with Cancer. Cancer Therapy and Reserach Center, San Antonio TX, and Pro-Neuron, Inc., Gaithesburg, MD., to be presented at 10th NCI-EORTC Symposium on New Drugs in Cancer Therapy, June 16-19, 1998
CD Britten, EK Rowinsky, SS Agarwala, SD Baker, J Eckardt, S Diab, M Dugan, P Reidenberg, P Statkevich, A Marco, A Loomba, K Forral, M Kraynak, DD Von Hoff, and SG Eckhardt. A Phase I Safety and Pharmacokinetic (PK) Study of Temozolomide in Combination with Cisplatin. Cancer Therapy and Research Center, San Antonio TX, University of Pittsburgh, Pittsburgh PA, and Schering-Plough, Kenilworth NJ

American Society of Clinical Oncology meeting, 1999

SG Diab, RM Elledge, and GM Clark. Favorable biological characteristics and clinical outcome in elderly patients with invasive ductal carcinoma (IDC) of the breast. (poster discussion)
W Tan, C. Tin-U, M Villalona, L Ochoa, M Kalidas, R Drengler, P Khoury, T Herman, A W Vally, B Brady, E Rowinsky, S Diab. Phase I study of weekly paclitaxel in combination with daily cisplatin and radiation in locally advanced head and neck and non-small cell lung carcinoma and esophageal carcinoma.
R Sun Young, SG Diab, C Britten, G Eckhardt, L Hammond, R Elledge, L Siu, S Sharma, M Hidalgo, C Aylesworth, B Razvillas, M Kraynak, S Baker, R Smith, S Averbuch, D Von Hoff, and E Rowinsky. Determination of the Variables affecting the Clearence of the Novel Thymidylate Synthase (TS) Inhibitor ZD9331
E Rowinsky, T Johnson, C Geyer, SG Eckhardt, L Smetzer, J Coyle, R Drengler, S Diab, R De Jager, and D Von Hoff. DX-8951f, a hexacyclic captothecin (CPT) analog on a daily x 5 schedule: a phase I and pharmacokinetic study.
T Johnson, L Hammond, R Johnson, R Drengler, SG Eckhardt, J neumanitis, M Villalona, T Williams, S Diab, J Walling, C Simmon, D Von Hoff, and E Rowinsky. Phase I and pharmacokinetic study of the multitargeted Antifol LY231514 (MTA) in combination with irinotecan (CPT-11).

Miscellaneous meetings

Andersen J, Shelly C, Diab S. Receptor-Independent Augmentation of Cytokine-Induced Endothelial Cell Tissue Factor Production by Flavone Acetic Acid may Promote Vascular Thrombosis. Presented at the American Society of Hematology Meeting, 1991
Andersen J, Shelly C, Diab S. Flavone Acetic Acid Augments Cytokine-Stimulated Endothelial Cell Tissue Factor Production by a Receptor-Independent Mechanism. Presented at Symposium on the Molecular Biology of Endothelial Cells, Keystone, 1992
Diab S, Shelly C, Andersen J. Cytokine-Stimulated Human Endothelial Cells Bind IGG from Patients with Thrombotic Thrombocytopenic Purpura (TTP) and Hemolytic Uremic Syndrome (HUS). Presented at American Collage of Physicians National Meeting, 1992
Diab SG, deMoor CA, Clark GM, Elledge RM. Prognostic Factors in Breast Cancer Patients with 10 or more Positive Lymph Nodes. Abstract. Presented at 5th Annual Symposium on Cancer Research, San Antonio, 1995